FUJIFILM Toyama Chemical Co., Ltd.
Address
(ZIP code:930-8508）2-4-1 Shimookui Toyama-city Toyama ／(ZIP code:931-8334）1-8-70 Chiharazaki Toyama-city Toyama
Tel:+81-76-432-3136(information)
Shionozaki, Shibata
We have developed a number of new drugs, β-lactam antibiotics, and have accumulated a number of technologies and expertise, including industrialized data and improved manufacturing processes. Leveraging over 40 years of expertise in anti-infective drugs, we have recently focused on contract manufacturing as the only company capable of manufacturing sterile penicillin antibiotics products in Japan.
We also design, process-development, and consignment of investigational product manufacturing and commercial production of drug-delivery-system (DDS) techniques, such as lipid-nanoparticle (LNP) and liposome-based formulations.
All outsourced services have specialized services, which allow for smooth response.
| Production category | Large classification | Middle classification | Form of drug | Sub classification | Feature of the form | Capacity of commission (per year) | Contractable process | Main production machine | Production techniques | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Commissioned development | Investigational drug manufacturing | Commercial production | Packaging | |||||||||
| GMP manufacturing | Pharmaceutical formulation | Small molecule drugs（without highly potent drugs） | Tablets | Plain tablets | PTP package | 50 million tablets | ● | ● | ・Pulverizer ・Fluidized bed granulation ・Coating dryer ・Blender ・Tablet press ・Coating machine ・Tablet printing machine ・Capsule filling machine ・Packaging and filling machine ・Appearance tester ・PTP packaging machine ・Bottle filling machine ・Pillow packaging machine etc. | ・Bitter masking technology ・Tablet miniaturization technology | ||
| Granule | Granules | Bottle filling and packaging | ー | ● | ● | |||||||
| Powder | 4 tons combined with the number 2 | ● | ● | |||||||||
| Tablets | Plain tablets | PTP and bottle-filled packaging | 150 million tablets | ● | ● | ・Pulverizer ・Fluidized bed granulation ・Coating dryer ・Stirring granulator ・Extrusion granulator ・Needler ・Dry granulator ・Blender ・Tablet press ・Coating machine ・Tablet printing machine ・Capsule filling machine ・Appearance tester ・PTP packaging machine ・Bottle filling machine ・Pillow packaging machine etc. | ||||||
| Granule | Granules | Bottle-filled packaging | ー | ● | ● | |||||||
| Powder | 10 tons together with the number 6 | ● | ● | |||||||||
| Injection | Vial | Vial lyophilized formulation Tray lyophilized formulation | 5 million vials | ● | ● | ・Preparation of drug solution ・Vial filling line (cleaning, sterilization, filling) ・Rubber plug sterilizer ・Lyophilizer ・Seaming machine ・Washer ・Appearance tester ・Packaging machine (Labeler, Cartner) | ・Sterilization technology and microbiological control technology ・High-efficiency lyophilization technology (industry's fastest freeze-drying cycle) ・Developed in-house double bag | |||||
| Bag | Powder, Liquid Double Fill | 3 million bags | ● | ● | ・Preparation of saline ・Bag punching and liquid filling machine ・Sterilizer ・Powder filling machine ・Pinhole inspection machine ・Barrier attaching machine ・Packaging machine (Labeler, Cartner) | |||||||
| API/Intermediate | Subject to Negotiation | ● | ・Reaction facility (～3,500 L:GL、SUS) ・Filter ・Centrifuge ・Dryer etc. | ・Highly Reactive Coupling Technique Using Metal Catalysis ・Technologies for improving reaction efficiency by flow photosynthesis (shortening routes and reducing impurities) | ||||||||
| ● | ・Reaction facility (～8,000 L:GL、SUS、HAS) ・Filter ・Centrifuge ・Dryer etc. | |||||||||||
| Pharmaceutical formulation | Other polymers | Injection | Vial | ● | ● | ● | ・Liquid preparation facility ・Filtration system ・Vial filling line (cleaning, sterilization, filling) etc. | ・Research and development of liposomal formulations using advanced nanodispersion technology, analysis technology, and process technology ・Mass production facilities and physical containment facilities for Fujifilm's original design and development | ||||
| ● | ● | ● | ・Research and development of lipid nanoformulations using advanced nanodispersion technology, analysis technology, and process technology ・Mass production facilities and physical containment facilities for Fujifilm's original design and development | |||||||||
| Investigational new drug | ● | ● | ● | ・Research and development of liposomal formulations using advanced nanodispersion technology, analysis technology, and process technology ・Mass production facilities and physical containment facilities for Fujifilm's original design and development | ||||||||
| ● | ● | ● | ・Research and development of lipid nanoformulations using advanced nanodispersion technology, analysis technology, and process technology ・Mass production facilities and physical containment facilities for Fujifilm's original design and development | |||||||||
